Peer-Reviewed Study of Vaccinated Versus Unvaccinated Children
Results: Vaccinated children were significantly less likely than the unvaccinated to have been diagnosed with chickenpox and pertussis, but significantly more likely to have been diagnosed with other infections, allergies and NDDs (defined as Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, and/or a learning disability).
Chronic Illness Detail:
- Vaccinated children were significantly more likely than the unvaccinated to have been diagnosed with the following chronic illnesses:
- 7-fold higher odds of any neurodevelopmental disorder (i.e., learning disability, ADHD, or ASD)
- 2-fold increase in Autism Spectrum Disorder (“ASD”)
- 2-fold increase in ADHD
- 2-fold increase in learning disabilities
- 1-fold increase in allergic rhinitis
- 9-fold increase in other allergies
- 9-fold increase in eczema/atopic dermatitis
- 4-fold increase in any chronic ?illness
- No significant differences were observed with regard to cancer, chronic fatigue, conduct disorder, Crohn’s disease, depression, Types 1 or 2 diabetes, encephalopathy, epilepsy, hearing loss, high blood pressure, inflammatory bowel disease, juvenile rheumatoid arthritis, obesity, seizures, and Tourette’s syndrome. However, larger samples would be needed to detect group differences in these less common conditions.
Acute Illness Detail:
- Vaccinated children were significantly less likely than unvaccinated children to have had chickenpox or whooping cough (p<0.001).
- Vaccinated children had a 3.8-fold increased odds of middle ear infections and a 5.9-fold increased odds of being diagnosed with pneumonia compared to unvaccinated children.
- No significant differences were seen between the two groups with regard to Hepatitis A or B, high fever in the past 6 months, measles, mumps, meningitis (viral or bacterial), influenza, or rotavirus.
Vaccination, Preterm Birth and Neurodevelopmental Disorders (NDDs):
In regression analyses, vaccination was associated with a significant 3.1-fold increased odds of neurodevelopmental disorders (combining the diagnoses of ASD, ADHD, and learning disability), after controlling for other factors. An important detail emerged regarding a possible synergism between vaccination and preterm birth. In a final adjusted statistical model, vaccination but not preterm birth remained associated with NDD, as defined, while the interaction of preterm birth and vaccination was associated with a 6.6-fold increased odds of NDD (95% Confidence Interval: 2.8, 15.5).More